A Chevrolet Camaro was eastbound on the 8500 block of Olive Drive when it struck the bicyclist crossing northbound in the Nos. 1 and 2 lanes, according to police.
The bike rider suffered moderate to major injuries, police said.
The crash happened at around 5:20 a.m., when it was still dark outside. Official sunrise Tuesday was 7:09 a.m., according to Eyewitness News weathercaster Aaron Perlman.
Police warned cyclists to wear helmets and use a headlamp and reflectors when it's dark outside. Police didn't say whether this cyclist took those precautions.
Police haven't released the name of either party involved.