"Can't Hold Us," also by Macklemore & Lewis, was iTunes' fifth best-selling song.
Robin Thicke's "Blurred Lines," ''Radioactive" by Imagine Dragons and Pink's "Just Give Me a Reason" ranked second, third and fourth on iTunes.
Justin Timberlake's "The 20/20 Experience" is the best-selling album - so far.
Beyonce's new album was released just last week, but it's already the second best-selling album on iTunes this year, selling more than 617,000 units in three days.
Albums from Imagine Dragons, Jay Z and Drake round out the top 5.
"Skyfall" is the year's top-selling movie and "Breaking Bad" is the leading TV show.
Candy Crush Saga, King.com Limited is the top free app for iPhones and iPads. Candy Crush is also the top paid app for iPads. The top paid app for iPhones is Minecraft, Pocket Edition, Mojang.