The victims are 33-year-old Raymond Tse and his daughter, 1-year-old Chloe Tse.
The girl's grandfather also suffered critical injuries. Her mother was able to escape.
Fire officials say crews were called to the scene around 1:30 a.m. Friday. The mother had come home from work and was awake, but the girl, her father and grandfather were asleep.
Fire officials say the mother smelled smoke and called 911.
Crews put out the fire around 2 a.m., but were delayed from entering the home by a metal gate they had to cut through.
The cause of the fire remains under investigation. The home did have working smoke detectors.