There are no injuries.
The California Department of Transportation says the southbound tractor-trailer hauling onions slammed into 50 feet of guardrail and took out a concrete head rail on a ditch crossing at Nelson Road about 90 miles north of Sacramento.
Pacific Gas & Electric power lines were also taken down in the late Thursday crash.
Caltrans says a detour around the crash site is adding 25 minutes to commute times.
The highway is expected to reopen by 11 a.m. Friday.