Democratic Sen. Max Baucus of Montana says Lew has answered the committee's questions "in a thorough and fully transparent manner" and the committee has conducted a "thorough review" of the nominee.
Lew would succeed Timothy Geithner in President Barack Obama's second-term Cabinet.
Some of the toughest questions he faced during his confirmation hearing dealt with his short time at Citibank. Lew was a top executive during the height of the financial crisis.
On policy matters, he addressed Europe's debt crisis, U.S.-China relations and the 2010 financial regulatory overhaul.